We're in constant pursuit of breakthroughs that improve patients' lives. We create innovations every day to make the world a healthier place. This was Charles Pfizer's initial vision, and it still holds true today. Evidence confirms what intuition tells us: that purpose-driven companies achieve more, are more creative, recruit and maintain the best professionals, and know how to harness the power of those individuals. Pfizer's purpose—Breakthroughs that transform patients' lives—fuels everything we do and shows our passion for building on our legacy as one of the most meaningful contributors of good to the world. Each word in our purpose has importance and embodies the value we work to bring to patients and society. Our purpose makes certain that patients remain at the centre of all we do. We live our purpose by seeking the best science in the world, working with others in the healthcare system to increase access to our medicines, employing digital technologies to advance our drug discovery and development, as well as patient outcomes, and spearheading the conversation to advocate for pro-innovation/pro-patient policies. Every decision we make, and every step we take is done with the patient in mind—and to foster an environment where breakthroughs can flourish.